2. Gene
  3. Pde12 - phosphodiesterase 12 Gene

Pde12 - phosphodiesterase 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2-PDE; 2'-PDE; E430028B21Rik

Gene ID: 211948 | Gene type: protein coding

About Pde12

Chromosome 14: 26,381,113-26,391,038 reverse strand.GRCm39:CM001007.3

This gene has 1 transcript (splice variant), 204 orthologues, 5 paralogues and is associated with 6 phenotypes. Ubiquitous expression in thymus adult (RPKM 1.), ovary adult (RPKM 8.2) and 28 other tissues.

Summary

Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to cytokine stimulus; and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within mRNA processing. Located in mitochondrion. Is expressed in brain; foregut; genitourinary system; and skin. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Apr 2022]

Pde12 Products(1)

mRNA Protein Name
NM_178668.4 NP_848783.3 2',5'-phosphodiesterase 12

Pde12 Protein Structure

EEP

EEP: cl00490 (297 - 606)

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  • 608 a.a.
Protein Preferred Names Protein Names

2',5'-phosphodiesterase 12

2'-phosphodiesterase

mitochondrial deadenylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124768 PDE12-IN-3 Inhibitor 99.43% Unkown
HY-117318 PDE12-IN-1 Inhibitor 99.23% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde12 NCBI NCBI:201626