Pde12 - phosphodiesterase 12 Gene
Also Known as 2-PDE; 2'-PDE; E430028B21Rik
Species: Mus musculus
About Pde12
This gene has 1 transcript (splice variant), 204 orthologues, 5 paralogues and is associated with 6 phenotypes. Ubiquitous expression in thymus adult (RPKM 1.), ovary adult (RPKM 8.2) and 28 other tissues.
Summary
Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to cytokine stimulus; and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within mRNA processing. Located in mitochondrion. Is expressed in brain; foregut; genitourinary system; and skin. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Apr 2022]
Pde12 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_178668.4 | NP_848783.3 | 2',5'-phosphodiesterase 12 |
Pde12 Protein Structure
EEP: cl00490 (297 - 606)
- 0
- 100
- 200
- 300
- 400
- 500
- 608 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
2',5'-phosphodiesterase 12 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-117318 | PDE12-IN-1 | Inhibitor | 99.11% | Unkown |
| HY-124768 | PDE12-IN-3 | Inhibitor | 98.02% | Unkown |
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