Tac1 - tachykinin 1 Gene

Also Known as SP; NK1; NK-1; Nkna; PPTA; PPT-A; 4930528L02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21333

Summary

Predicted to enable Neurokinin Receptor binding activity and receptor ligand activity. Acts upstream of or within several processes, including cellular response to nerve growth factor stimulus; response to pain; and sensory perception of pain. Located in axon; extracellular region; and neuronal cell body. Is expressed in several structures, including alimentary system; integumental system; limb; nervous system; and sensory organ. Orthologous to human TAC1 (tachykinin precursor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tac1 Products (2)

mRNA Protein Name
NM_001311060.2 NP_001297989.1 protachykinin-1 isoform 2 precursor
NM_009311.3 NP_033337.1 protachykinin-1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31146259 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to nerve growth factor stimulus IDA
IDA: Inferred from direct assay
24760869 MGI
acts upstream of or within inflammatory response IDA
IDA: Inferred from direct assay
15159534 MGI
acts upstream of or within response to pain IMP
IMP: Inferred from mutant phenotype
11805341 MGI
acts upstream of or within sensory perception of pain IMP
IMP: Inferred from mutant phenotype
9537322 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
1317267 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
9537322 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
9853118 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protachykinin-1

  • neurokinin 1

  • neurokinin A

  • preprotachykinin A

  • substance P

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14136 TAC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18639 Tac1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25124 Tac1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tac1 NCBI NCBI:6863