Tacr1 - tachykinin receptor 1 Gene

Mus musculus

Also known as Spr; Nk1r; Tac1r

Gene ID: 21336 | Gene type: protein coding

About Tacr1

Chromosome 6: 82,379,315-82,537,085 forward strand.GRCm39:CM000999.3

This gene has 3 transcripts (splice variants), 270 orthologues, 55 paralogues and is associated with 34 phenotypes. Low expression observed in reference dataset.

Summary

This gene encodes the receptor for the tachykinin, substance P, also referred to as neurokinin 1. This gene belongs to a gene family of tachykinin receptors which are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This receptor has been associated with nitric oxide formation, and it has been localized to cholinergic and nitrergic neurons as well as on smooth muscle cells. [provided by RefSeq, Mar 2010]

Tacr1 Products(1)

mRNA	Protein	Name
NM_009313.5	NP_033339.2	substance-P receptor

Tacr1 Protein Structure

7tm_GPCRs

0
100
200
300
407 a.a.

Protein Preferred Names

Protein Names

substance-P receptor

Nk1 receptor	neurokinin receptor 1
substance P receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14143	TACR1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14144	Tacr1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14145	Tacr1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tacr1	NCBI	NCBI:6869

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