Adgrg6 - adhesion G protein-coupled receptor G6 Gene

Also Known as DREG; Gm222; Gpr126; 1190004A11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215798

Summary

Enables laminin binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; heart trabecula formation; and myelination in peripheral nervous system. Predicted to be located in cell surface; cytoplasm; and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including heart; lung; otocyst; paraxial mesenchyme; and spleen. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6). [provided by Alliance of Genome Resources, Apr 2022]

Adgrg6 Products (1)

mRNA Protein Name
NM_001002268.3 NP_001002268.1 adhesion G-protein coupled receptor G6 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables laminin binding IMP
IMP: Inferred from mutant phenotype
25695270 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
27501152 MGI
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
27501152 MGI
involved in heart trabecula formation IMP
IMP: Inferred from mutant phenotype
24082093 MGI
involved in mitochondrion organization IMP
IMP: Inferred from mutant phenotype
24082093 MGI
involved in myelination in peripheral nervous system IMP
IMP: Inferred from mutant phenotype
24227709 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G-protein coupled receptor G6

  • G protein coupled receptor Gpr126

  • G-protein coupled receptor 126

  • developmentally regulated G-protein-coupled receptor

  • probable G-protein coupled receptor 126

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175232 GL64 98.80% Unkown
HY-RS00359 ADGRG6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21817 Adgrg6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28333 Adgrg6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrg6 NCBI NCBI:57211