Tfdp1 - transcription factor Dp 1 Gene
Also Known as Dp1; Drtf1
Species: Mus musculus
Gene Type: protein coding
Gene ID: 21781
Summary
Enables DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of fat cell proliferation. Acts upstream of or within anoikis; epidermis development; and regulation of cellular macromolecule biosynthetic process. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and retina. Orthologous to several human genes including TFDP1 (transcription factor Dp-1). [provided by Alliance of Genome Resources, Apr 2022]
Tfdp1 Products (32)
| mRNA | Protein | Name |
|---|---|---|
| NM_001291765.2 | NP_001278694.1 | transcription factor Dp-1 isoform 1 |
| NM_001291766.2 | NP_001278695.1 | transcription factor Dp-1 isoform 2 |
| NM_001291768.2 | NP_001278697.1 | transcription factor Dp-1 isoform 2 |
| NM_001358991.2 | NP_001345920.1 | transcription factor Dp-1 isoform 2 |
| NM_001413797.1 | NP_001400726.1 | transcription factor Dp-1 isoform 2 |
| NM_001413798.1 | NP_001400727.1 | transcription factor Dp-1 isoform 2 |
| NM_001413799.1 | NP_001400728.1 | transcription factor Dp-1 isoform 2 |
| NM_001413800.1 | NP_001400729.1 | transcription factor Dp-1 isoform 2 |
| NM_001413801.1 | NP_001400730.1 | transcription factor Dp-1 isoform 3 |
| NM_001413802.1 | NP_001400731.1 | transcription factor Dp-1 isoform 2 |
| NM_001413803.1 | NP_001400732.1 | transcription factor Dp-1 isoform 2 |
| NM_001413804.1 | NP_001400733.1 | transcription factor Dp-1 isoform 4 |
| NM_001413805.1 | NP_001400734.1 | transcription factor Dp-1 isoform 5 |
| NM_001413806.1 | NP_001400735.1 | transcription factor Dp-1 isoform 2 |
| NM_001413807.1 | NP_001400736.1 | transcription factor Dp-1 isoform 2 |
| NM_001413808.1 | NP_001400737.1 | transcription factor Dp-1 isoform 2 |
| NM_001413809.1 | NP_001400738.1 | transcription factor Dp-1 isoform 2 |
| NM_001413810.1 | NP_001400739.1 | transcription factor Dp-1 isoform 2 |
| NM_001413811.1 | NP_001400740.1 | transcription factor Dp-1 isoform 2 |
| NM_001413812.1 | NP_001400741.1 | transcription factor Dp-1 isoform 2 |
| NM_001413813.1 | NP_001400742.1 | transcription factor Dp-1 isoform 2 |
| NM_001413814.1 | NP_001400743.1 | transcription factor Dp-1 isoform 2 |
| NM_001413815.1 | NP_001400744.1 | transcription factor Dp-1 isoform 6 |
| NM_001413816.1 | NP_001400745.1 | transcription factor Dp-1 isoform 2 |
| NM_001413817.1 | NP_001400746.1 | transcription factor Dp-1 isoform 2 |
| NM_001413818.1 | NP_001400747.1 | transcription factor Dp-1 isoform 2 |
| NM_001413819.1 | NP_001400748.1 | transcription factor Dp-1 isoform 1 |
| NM_001413820.1 | NP_001400749.1 | transcription factor Dp-1 isoform 2 |
| NM_001413821.1 | NP_001400750.1 | transcription factor Dp-1 isoform 2 |
| NM_001413822.1 | NP_001400751.1 | transcription factor Dp-1 isoform 1 |
| NM_001413823.1 | NP_001400752.1 | transcription factor Dp-1 isoform 1 |
| NM_009361.4 | NP_033387.1 | transcription factor Dp-1 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA-binding transcription factor activity |
IDA
IDA: Inferred from direct assay
|
14667810 | MGI |
| enables cis-regulatory region sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
15448153 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
11331592 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within anoikis |
IDA
IDA: Inferred from direct assay
|
14667810 | MGI |
| acts upstream of or within epidermis development |
IMP
IMP: Inferred from mutant phenotype
|
15448153 | MGI |
| involved in negative regulation of fat cell proliferation |
IMP
IMP: Inferred from mutant phenotype
|
20176812 | MGI |
| acts upstream of or within positive regulation of DNA-templated transcription |
IDA
IDA: Inferred from direct assay
|
11331592 | MGI |
| acts upstream of or within positive regulation of transcription by RNA polymerase II |
IGI
IGI: Inferred from genetic interaction
|
7797074 | MGI |
| acts upstream of or within regulation of DNA biosynthetic process |
IMP
IMP: Inferred from mutant phenotype
|
15448153 | MGI |
| acts upstream of or within regulation of DNA-templated transcription |
IDA
IDA: Inferred from direct assay
|
14667810 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
25940086 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
10082561 | MGI |
| part of transcription regulator complex |
IDA
IDA: Inferred from direct assay
|
10082561 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transcription factor Dp-1 |
|
|