Top3a - topoisomerase (DNA) III alpha Gene
Species: Mus musculus
Summary
Predicted to enable DNA Topoisomerase type I (single strand cut, ATP-independent) activity and single-stranded DNA binding activity. Predicted to be involved in DNA topological change; chromosome separation; and mitochondrial DNA metabolic process. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; cardiovascular system; genitourinary system; gut; and nervous system. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Orthologous to human TOP3A (DNA Topoisomerase III alpha). [provided by Alliance of Genome Resources, Apr 2022]
Top3a Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_009410.3 | NP_033436.1 | DNA topoisomerase 3-alpha |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
DNA topoisomerase 3-alpha |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14898 | TOP3A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21791 | Top3a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28307 | Top3a Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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