Abra - actin-binding Rho activating protein Gene

Also Known as STARS; C130068O12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223513

Summary

Enables actin binding activity. Involved in positive regulation of DNA-binding transcription factor activity and positive regulation of Rho protein signal transduction. Acts upstream of or within positive regulation of transcription by RNA polymerase II and protein import into nucleus. Located in actin Cytoskeleton and myofibril. Is expressed in embryo; heart; hindlimb muscle; and skeletal muscle. Orthologous to human ABRA (actin binding Rho activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Abra Products (1)

mRNA Protein Name
NM_175456.4 NP_780665.1 actin-binding Rho-activating protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
11983702 MGI
Biological Process GO Annotation Evidence References Source
involved in actin cytoskeleton organization IDA
IDA: Inferred from direct assay
11983702 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15798203 MGI
involved in positive regulation of Rho protein signal transduction IDA
IDA: Inferred from direct assay
11983702 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17194709 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17194709 MGI
acts upstream of or within protein import into nucleus IDA
IDA: Inferred from direct assay
15798203 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17194709 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17194709 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
11983702 MGI
located in myofibril IDA
IDA: Inferred from direct assay
17194709 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin-binding Rho-activating protein

  • striated muscle activator of Rho-dependent signaling

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00111 ABRA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19114 Abra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25604 Abra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abra NCBI NCBI:137735