Eif3l - eukaryotic translation initiation factor 3, subunit L Gene

Also Known as PAF67; D15N1e; Eif3ip; Eif3eip; HSP-66Y; Eif3s6ip; 0610011H21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223691

Summary

Contributes to translation initiation factor activity. Involved in translational initiation. Located in fibrillar center and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. Is expressed in thymus primordium. Orthologous to human EIF3L (eukaryotic translation initiation factor 3 subunit L). [provided by Alliance of Genome Resources, Apr 2022]

Eif3l Products (1)

mRNA Protein Name
NM_145139.2 NP_660121.2 eukaryotic translation initiation factor 3 subunit L

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11592397 MGI
contributes to translation initiation factor activity IDA
IDA: Inferred from direct assay
17581632 MGI
Biological Process GO Annotation Evidence References Source
involved in translational initiation IDA
IDA: Inferred from direct assay
17581632 MGI
Cellular Component GO Annotation Evidence References Source
part of eukaryotic translation initiation factor 3 complex IDA
IDA: Inferred from direct assay
17581632 MGI
located in fibrillar center IDA
IDA: Inferred from direct assay
11592397 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
11592397 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
11592397 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 3 subunit L

  • 66 kDa tyrosine-rich heat shock protein

  • 67 kDa polymerase-associated factor

  • eukaryotic translation initiation factor 3 subunit 6-interacting protein

  • eukaryotic translation initiation factor 3 subunit E-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04268 EIF3L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21563 Eif3l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28081 Eif3l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif3l NCBI NCBI:51386