Trim31 - tripartite motif-containing 31 Gene

Also Known as RNF; HCG1; HCGI

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224762

Summary

Predicted to enable transcription coactivator activity and ubiquitin protein Ligase activity. Involved in innate immune response and negative regulation of viral entry into host cell. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in Peyer's patch; gut; and testis. Orthologous to human TRIM31 (tripartite motif containing 31). [provided by Alliance of Genome Resources, Apr 2022]

Trim31 Products (1)

mRNA Protein Name
NM_146077.2 NP_666189.1 E3 ubiquitin-protein ligase TRIM31

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
27929086 MGI
Biological Process GO Annotation Evidence References Source
involved in antiviral innate immune response IMP
IMP: Inferred from mutant phenotype
27992402 MGI
involved in defense response to virus IMP
IMP: Inferred from mutant phenotype
27992402 MGI
involved in innate immune response IDA
IDA: Inferred from direct assay
18248090 MGI
involved in negative regulation of NLRP3 inflammasome complex assembly IDA
IDA: Inferred from direct assay
27929086 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
18248090 MGI
involved in protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
27929086 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
27929086 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM31

  • RING-type E3 ubiquitin transferase TRIM31

  • tripartite motif-containing protein 31

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15036 TRIM31 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21960 Trim31 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28477 Trim31 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim31 NCBI NCBI:11074