Lamc1 - laminin, gamma 1 Gene

Also Known as Lamb2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226519

Summary

Enables glycosphingolipid binding activity. Acts upstream of or within neuron projection development. Located in basement membrane and synaptic cleft. Part of laminin-10 complex. Is active in neuromuscular junction. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human LAMC1 (laminin subunit gamma 1). [provided by Alliance of Genome Resources, Apr 2022]

Lamc1 Products (1)

mRNA Protein Name
NM_010683.2 NP_034813.2 laminin subunit gamma-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycosphingolipid binding IDA
IDA: Inferred from direct assay
19118221 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12243745 MGI
Biological Process GO Annotation Evidence References Source
involved in chromatin organization IMP
IMP: Inferred from mutant phenotype
27234308 MGI
involved in gene expression IMP
IMP: Inferred from mutant phenotype
27234308 MGI
involved in hair cell differentiation IMP
IMP: Inferred from mutant phenotype
27234308 MGI
involved in hair follicle cell proliferation IMP
IMP: Inferred from mutant phenotype
27234308 MGI
involved in hair follicle morphogenesis IMP
IMP: Inferred from mutant phenotype
27234308 MGI
acts upstream of or within neuron projection development IDA
IDA: Inferred from direct assay
19118221 MGI
involved in tissue morphogenesis IMP
IMP: Inferred from mutant phenotype
27234308 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
1292752 MGI
part of laminin-10 complex IPI
IPI: Inferred from physical interaction
9299121 MGI
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
9396756 MGI
is active in synaptic cleft IDA
IDA: Inferred from direct assay
9396756 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit gamma-1

  • S-LAM gamma

  • S-laminin subunit gamma

  • laminin B2 chain

  • laminin-1 subunit gamma

  • laminin-10 subunit gamma

  • laminin-11 subunit gamma

  • laminin-2 subunit gamma

  • laminin-3 subunit gamma

  • laminin-4 subunit gamma

  • laminin-6 subunit gamma

  • laminin-7 subunit gamm

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07506 LAMC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20440 Lamc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26949 Lamc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamc1 NCBI NCBI:3915