Tubb4b - tubulin, beta 4B class IVB Gene

Also Known as Tubb2c; Tubb2c1; 4930542G03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227613

Summary

Predicted to enable GTP binding activity and double-stranded RNA binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization and mitotic cell cycle. Located in myelin sheath. Is expressed in brain ependyma; epithelial layer of oviduct; nasal epithelium; respiratory system epithelium; and seminiferous tubule. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness. Orthologous to human TUBB4B (tubulin beta 4B class IVb). [provided by Alliance of Genome Resources, Apr 2022]

Tubb4b Products (1)

mRNA Protein Name
NM_146116.2 NP_666228.1 tubulin beta-4B chain

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
Cellular Component GO Annotation Evidence References Source
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-4B chain

  • novel tubulin protein

  • tubulin beta-2C chain

  • tubulin, beta 2C

  • tubulin, beta 2c1

  • tubulin, beta, 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15256 TUBB4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21214 Tubb4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27730 Tubb4b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb4b NCBI NCBI:10383