LAMB4 - laminin subunit beta 4 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 22798

About LAMB4

Cytogenetic location: 7q31.1 Genomic coordinates (GRCh38): 7:108,011,662-108,130,361 (from NCBI)

This gene has 8 transcripts (splice variants), 128 orthologues and 27 paralogues. Biased expression in skin (RPKM 11.6), placenta (RPKM 1.2) and 1 other tissue.

Summary

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to be located in basement membrane; extracellular region; and membrane. Predicted to be part of laminin complex. [provided by Alliance of Genome Resources, Apr 2022]

LAMB4 Products (4)

mRNA Protein Name
NM_001318046.2 NP_001304975.1 laminin subunit beta-4 isoform 1 precursor
NM_001318047.2 NP_001304976.1 laminin subunit beta-4 isoform 2 precursor
NM_001318048.2 NP_001304977.1 laminin subunit beta-4 isoform 3 precursor
NM_007356.3 NP_031382.2 laminin subunit beta-4 isoform 1 precursor

LAMB4 Protein Structure

Laminin_N

Laminin_N: Laminin N-terminal (Domain VI) (28 - 263)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (265 - 320)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (332 - 383)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (395 - 452)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (455 - 503)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (506 - 544)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (769 - 814)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (817 - 865)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (911 - 967)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (970 - 1019)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1022 - 1077)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1080 - 1121)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1128 - 1168)

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  • 1761 a.a.
Protein Preferred Names Protein Names

laminin subunit beta-4

  • laminin beta-1-related protein

Related Diseases

Diseases Alias
Diverticulitis
Diverticulitis Of Colon

  • Colonic Diverticular Disease

  • Diverticulitis, Colonic

  • Diverticular Disease Of Colon
Macular Degeneration, Age-Related, 13

  • Age Related Macular Degeneration 13

  • ARMD13

  • Macular Degeneration, Age-Related, 13, Susceptibility To

  • Macular Degeneration, Age-Related, Type 13
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07505 LAMB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown