Gpr171 - G protein-coupled receptor 171 Gene

Also Known as H963; A630006E05; F730001G15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 229323

About Gpr171

Chromosome 3: 59,003,869-59,009,242 reverse strand.GRCm39:CM000996.3

This gene has 1 transcript (splice variant), 170 orthologues and 6 paralogues. Biased expression in thymus adult (RPKM 4.5), spleen adult (RPKM 2.7) and 6 other tissues.

Summary

Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within negative regulation of myeloid cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human GPR171 (G protein-coupled receptor 171). [provided by Alliance of Genome Resources, Apr 2022]

Gpr171 Products (1)

mRNA Protein Name
NM_173398.3 NP_775574.1 G-protein coupled receptor 171

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled peptide receptor activity IDA
IDA: Inferred from direct assay
24043826 MGI
enables neuropeptide binding IDA
IDA: Inferred from direct assay
24043826 MGI
enables neuropeptide receptor activity IDA
IDA: Inferred from direct assay
24043826 MGI
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
24043826 MGI
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
24043826 MGI
acts upstream of or within negative regulation of myeloid cell differentiation IDA
IDA: Inferred from direct assay
23022127 MGI
acts upstream of or within negative regulation of myeloid cell differentiation IMP
IMP: Inferred from mutant phenotype
23022127 MGI
involved in regulation of feeding behavior IMP
IMP: Inferred from mutant phenotype
24043826 MGI
involved in regulation of sensory perception of pain IMP
IMP: Inferred from mutant phenotype
31308196 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
24043826 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Gpr171 Protein Structure

7tmA_GPR171

7tmA_GPR171: cd15167 (14 - 41)

7tmA_GPR171

7tmA_GPR171: cd15167 (14 - 295)

7tmA_GPR171

7tmA_GPR171: cd15167 (48 - 73)

7tmA_GPR171

7tmA_GPR171: cd15167 (86 - 116)

7tmA_GPR171

7tmA_GPR171: cd15167 (128 - 150)

7tmA_GPR171

7tmA_GPR171: cd15167 (175 - 204)

7tmA_GPR171

7tmA_GPR171: cd15167 (215 - 245)

7tmA_GPR171

7tmA_GPR171: cd15167 (263 - 288)

  • 0
  • 100
  • 200
  • 300
  • 319 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 171

  • probable G-protein coupled receptor 171

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112620 MS21570 99.93% Unkown
HY-116797 MS15203 99.40% Unkown
HY-P2210 BigLEN(mouse) 99.90% Unkown
HY-P2155 BigLEN(rat) 99.73% Unkown
HY-P2155A BigLEN(rat) TFA / Unkown
HY-P2210A BigLEN(mouse) TFA Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr171 NCBI NCBI:29909