USP24 - ubiquitin specific peptidase 24 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 23358

About USP24

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:55,066,359-55,215,364 (from NCBI)

This gene has 7 transcripts (splice variants), 164 orthologues and 71 paralogues. Ubiquitous expression in bone marrow (RPKM 9.9), lymph node (RPKM 9.7) and 25 other tissues.

Summary

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating Enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating Enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]

USP24 Products (1)

mRNA Protein Name
NM_015306.3 NP_056121.2 ubiquitin carboxyl-terminal hydrolase 24

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

USP24 Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (1689 - 2039)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2620 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 24

  • deubiquitinating enzyme 24

USP24 抗体

製品番号 製品名 アプリケーション 反応性
HY-P87132 USP24 Antibody (YA6825) WB, ICC/IF, IHC-P Human, Mouse

関連疾患

Diseases Alias
Non-Syndromic X-Linked Intellectual Disability 99

  • Mrx99

  • X-Linked Mental Retardation 99
Parkinson Disease, Late-Onset

  • Parkinson Disease

  • Parkinson'S Disease

  • PD

  • PARK

  • Parkinson Disease, Susceptibility To

  • Late Onset Parkinson'S Disease

  • Late Onset Parkinson Disease

  • Paralysis Agitans

  • Primary Parkinsonism

  • Idiopathic Parkinson Disease

  • Parkinson'S

  • Parkinson Disease, Late-Onset, Susceptibility To

  • Parkinson Disease, Age Of Onset, Modifier

  • Lewy Body Parkinson Disease

  • Idiopathic Parkinson'S Disease

  • Pd - [Parkinson Disease]

  • Parkinson Disease Nos

  • Parkinson, Nos

  • Primary Parkinson Disease
Fanconi Anemia, Complementation Group A

  • Fanconi Anemia

  • Fanconi Pancytopenia

  • Fanconi Anemia Complementation Group A

  • FANCA

  • Fa

  • Fanconi Panmyelopathy

  • Fanconi'S Anemia

  • Fanconi Anaemia

  • Fanconi'S Anaemia

  • Fanconi Hypoplastic Anemia

  • Estren-Dameshek Variant Of Fanconi Anemia

  • Estren-Dameshek Variant Of Fanconi Pancytopenia

  • Fanconi Anemia Estren-Dameshek Variant

  • Fanconis Anemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-111408 EOAI3402143 Inhibitor 98.11% Unkown
HY-176557 NCI677397 / Unkown
HY-RS15534 USP24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18555 Usp24 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25037 Usp24 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta USP24 VGNC VGNC:78743
Rattus norvegicus USP24 RGD RGD:1306799
Felis catus USP24 VGNC VGNC:66874
Mus musculus USP24 MGD MGI:1919936
Bos taurus USP24 VGNC VGNC:36717
Canis familiaris USP24 VGNC VGNC:48183
Others USP24 NCBI