Vac14 - Vac14 homolog (S. cerevisiae) Gene

Also Known as Trx; ingls; Tax1bp2; D8Wsu151e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 234729

Summary

Predicted to enable identical protein binding activity and kinase activator activity. Predicted to be involved in phosphatidylinositol biosynthetic process and positive regulation of kinase activity. Predicted to act upstream of or within response to osmotic stress. Predicted to be located in cytosol and vacuolar membrane. Predicted to be part of PAS complex. Predicted to be active in endosome membrane. Predicted to be extrinsic component of vacuolar membrane. Is expressed in embryo and extraembryonic component. Human ortholog(s) of this gene implicated in striatonigral degeneration. Orthologous to human VAC14 (VAC14 component of PIKfyve complex). [provided by Alliance of Genome Resources, Apr 2022]

Vac14 Products (1)

mRNA Protein Name
NM_146216.3 NP_666328.2 protein VAC14 homolog

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
22842785 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
22842785 MGI
Cellular Component GO Annotation Evidence References Source
is active in presynaptic endosome IDA
IDA: Inferred from direct assay
22842785 MGI
is active in presynaptic endosome IMP
IMP: Inferred from mutant phenotype
22842785 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein VAC14 homolog

  • Tax1 (human T-cell leukemia virus type I) binding protein 1

  • Tax1 (human T-cell leukemia virus type I) binding protein 2

  • vacuole morphology 14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15592 VAC14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22907 Vac14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29421 Vac14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vac14 NCBI NCBI:55697