Cdk10 - cyclin-dependent kinase 10 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 234854

Summary

The protein encoded by this gene belongs to the CDK (cyclin-dependent kinase) subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. The human ortholog has been shown to play a role in cellular proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 1. [provided by RefSeq, Jan 2010]

Cdk10 Products (2)

mRNA Protein Name
NM_194444.2 NP_919426.2 cyclin-dependent kinase 10 isoform 2
NM_194446.2 NP_919428.1 cyclin-dependent kinase 10 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cyclin-dependent protein kinase activity IGI
IGI: Inferred from genetic interaction
24218572 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24218572 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: Inferred from genetic interaction
24218572 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase 10

  • cell division protein kinase 10

  • cyclin-dependent kinase (CDC2-like) 10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18382 Cdk10 Mouse Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk10 NCBI NCBI:8558