Arid1b - AT rich interactive domain 1B (SWI-like) Gene

Also Known as Ardi1b; BAF250B; mKIAA1235; 8030481M12; 9330189K18Rik; B230217J03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 239985

Summary

Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Acts upstream of or within dendritic cell dendrite assembly; dendritic spine development; and neuron-neuron synaptic transmission. Located in nucleus. Part of nBAF complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Coffin-Siris syndrome 1 and autism spectrum disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome; Coffin-Siris syndrome 1; intellectual disability; lung non-small cell carcinoma; and neuroblastoma. Orthologous to human ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022]

Arid1b Products (1)

mRNA Protein Name
NM_001085355.1 NP_001078824.1 AT-rich interactive domain-containing protein 1B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23540691 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within dendritic cell dendrite assembly IMP
IMP: Inferred from mutant phenotype
26937011 MGI
acts upstream of or within dendritic spine development IMP
IMP: Inferred from mutant phenotype
26937011 MGI
acts upstream of or within neuron-neuron synaptic transmission IMP
IMP: Inferred from mutant phenotype
26937011 MGI
Cellular Component GO Annotation Evidence References Source
part of SWI/SNF superfamily-type complex IDA
IDA: Inferred from direct assay
24335282 MGI
part of nBAF complex IDA
IDA: Inferred from direct assay
23785148 MGI
located in nucleus IDA
IDA: Inferred from direct assay
26937011 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AT-rich interactive domain-containing protein 1B

  • ARID domain-containing protein 1B

  • AT rich interactive domain 1B (Swi1 like)

  • BRG1-associated factor 250b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00967 ARID1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19050 Arid1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25540 Arid1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arid1b NCBI NCBI:57492