Usp18 - ubiquitin specific peptidase 18 Gene

Also Known as UBP43; Ubp15; 1110058H21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 24110

Summary

Enables ISG15-specific protease activity. Acts upstream of or within response to bacterium and response to stilbenoid. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in cytosol and nucleus. Is expressed in axial skeleton; lung; and mandible. Orthologous to several human genes including USP18 (ubiquitin specific peptidase 18). [provided by Alliance of Genome Resources, Apr 2022]

Usp18 Products (1)

mRNA Protein Name
NM_011909.2 NP_036039.2 ubl carboxyl-terminal hydrolase 18

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ISG15-specific peptidase activity IMP
IMP: Inferred from mutant phenotype
16139798 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24533902 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
involved in response to stilbenoid IEP
IEP: Inferred from expression pattern
17086191 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubl carboxyl-terminal hydrolase 18

  • 43 kDa ISG15-specific protease

  • ISG15-specific-processing protease

  • ubiquitin specific protease 15

  • ubiquitin specific protease 18

  • ubl thioesterase 18

  • ubl thiolesterase 18

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-172969 ZHAWOC8655 Inhibitor 98.63% Unkown
HY-111458 GSK2643943A Inhibitor 98.79% Unkown
HY-RS17777 Usp18 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15528 USP18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24244 Usp18 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp18 NCBI NCBI:11274