Cdkn1c - cyclin-dependent kinase inhibitor 1C Gene

Also Known as p57; Kip2; p57KIP2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246060

Summary

Predicted to enable protein kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of cell cycle; positive regulation of transforming growth factor beta receptor signaling pathway; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including animal organ development; genetic imprinting; and regulation of exit from Mitosis. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Beckwith-Wiedemann syndrome; IMAGe syndrome; and hyperinsulinism. Orthologous to human CDKN1C (cyclin dependent kinase inhibitor 1C). [provided by Alliance of Genome Resources, Apr 2022]

Cdkn1c Products (3)

mRNA Protein Name
NM_001033757.1 NP_001028929.1 cyclin-dependent kinase inhibitor 1C isoform 1
NM_001033758.1 NP_001028930.1 cyclin-dependent kinase inhibitor 1C isoform 2
NM_182735.2 NP_877399.2 cyclin-dependent kinase inhibitor 1C isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19533683 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase inhibitor 1C

  • cyclin-dependent kinase inhibitor p57

  • p57KIP2 A3sh

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02413 CDKN1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20537 Cdkn1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27046 Cdkn1c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdkn1c NCBI NCBI:1028