Cyp7b1 - cytochrome P450 family 7 subfamily B member 1 Gene
Species: Rattus norvegicus
Summary
Predicted to enable oxysterol 7-alpha-hydroxylase activity. Involved in several processes, including circadian rhythm; memory; and response to cAMP. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Orthologous to human CYP7B1 (Cytochrome P450 family 7 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]
Cyp7b1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_019138.1 | NP_062011.1 | 25-hydroxycholesterol 7-alpha-hydroxylase |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in circadian rhythm |
IDA
IDA: Inferred from direct assay
|
12759897 | RGD |
| involved in memory |
IDA
IDA: Inferred from direct assay
|
17065445 | RGD |
| involved in response to cAMP |
IEP
IEP: Inferred from expression pattern
|
12029625 | RGD |
| involved in response to xenobiotic stimulus |
IEP
IEP: Inferred from expression pattern
|
12029625 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
25-hydroxycholesterol 7-alpha-hydroxylase |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS03488 | CYP7B1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18706 | Cyp7b1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25193 | Cyp7b1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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