Fgf9 - fibroblast growth factor 9 Gene

Also Known as Fgf4b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25444

Summary

Enables Fibroblast Growth Factor receptor binding activity and growth factor activity. Involved in several processes, including negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; positive regulation of vascular associated smooth muscle cell migration; and positive regulation of vascular associated smooth muscle cell proliferation. Acts upstream of or within positive regulation of MAPK cascade. Located in basement membrane and cytoplasm. Human ortholog(s) of this gene implicated in multiple synostoses syndrome. Orthologous to human FGF9 (Fibroblast Growth Factor 9). [provided by Alliance of Genome Resources, Apr 2022]

Fgf9 Products (1)

mRNA Protein Name
NM_012952.2 NP_037084.1 fibroblast growth factor 9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor receptor binding IPI
IPI: Inferred from physical interaction
15231666 RGD
enables growth factor activity IDA
IDA: Inferred from direct assay
15231666 RGD
Biological Process GO Annotation Evidence References Source
involved in fibroblast growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
15231666 RGD
involved in negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching IMP
IMP: Inferred from mutant phenotype
28259995 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
15231666 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
28259995 RGD
involved in positive regulation of vascular associated smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
28259995 RGD
involved in positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
28259995 RGD
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
17494997 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 9

  • FGF-9

  • GAF

  • HBGF-9

  • fibroblast growth factor 4b

  • glia-activating factor

Recombinant Fgf9 Proteins

Cat. No. Product Name Accession Purity
HY-P7178 FGF-9 Protein, Rat P36364 (L4-S208) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04907 FGF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174691 Human FGF9 mRNA / Unkown
HY-RS16698 Fgf9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23132 Fgf9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf9 NCBI NCBI:2254