Fosl2 - FOS like 2, AP-1 transcription factor subunit Gene

Also Known as Fra2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25446

Summary

Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in several processes, including conditioned taste aversion; response to estradiol; and response to progesterone. Located in nucleus. Biomarker of renal carcinoma. Orthologous to human FOSL2 (FOS like 2, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Fosl2 Products (2)

mRNA Protein Name
NM_001013146.2 NP_001013164.1 fos-related antigen 2 isoform 2
NM_012954.2 NP_037086.2 fos-related antigen 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12358739 RGD
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
10830307 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
21367864 RGD
Biological Process GO Annotation Evidence References Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
10987819 RGD
involved in conditioned taste aversion IEP
IEP: Inferred from expression pattern
18374904 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
12080023 RGD
involved in photoperiodism IEP
IEP: Inferred from expression pattern
16962714 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11340164 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
18280640 RGD
involved in response to cytokine IEP
IEP: Inferred from expression pattern
18280640 RGD
involved in response to estradiol IMP
IMP: Inferred from mutant phenotype
12021174 RGD
involved in response to hypoxia IMP
IMP: Inferred from mutant phenotype
15892448 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
17936518 RGD
involved in response to light stimulus IEP
IEP: Inferred from expression pattern
11146118 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
16373449 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
11113530 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
10934195 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
12080023 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
11295234 RGD
involved in transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
10830307 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fos-related antigen 2

  • FOS like 2, AP-1 trancription factor subunit

  • FRA-2

  • fos-like antigen 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18065 Fosl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05035 FOSL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24540 Fosl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fosl2 NCBI NCBI:2355