Rab4a - RAB4A, member RAS oncogene family Gene

Also Known as Rab4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25532

Summary

Enables several functions, including ATPase binding activity; GTP binding activity; and ionotropic glutamate receptor binding activity. Involved in Rab protein signal transduction. Located in cytoplasmic vesicle; cytosol; and plasma membrane. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB4A (RAB4A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab4a Products (1)

mRNA Protein Name
NM_013019.2 NP_037151.2 ras-related protein Rab-4A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables ATPase activator activity IDA
IDA: Inferred from direct assay
11062069 RGD
enables ATPase binding IPI
IPI: Inferred from physical interaction
11062069 RGD
enables GTP binding IDA
IDA: Inferred from direct assay
8037667 RGD
enables GTPase activity IDA
IDA: Inferred from direct assay
9169411 RGD
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
17194442 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23386062 RGD
enables syntaxin binding IPI
IPI: Inferred from physical interaction
11063739 RGD
Biological Process GO Annotation Evidence Références Source
involved in Rab protein signal transduction IMP
IMP: Inferred from mutant phenotype
9169411 RGD
Cellular Component GO Annotation Evidence Références Source
located in insulin-responsive compartment IDA
IDA: Inferred from direct assay
8366094 RGD
located in recycling endosome IDA
IDA: Inferred from direct assay
10468577 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-4A

  • Ras-related small GTP binding protein 4

Rab4a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Cross
Rab4a P05714 NISCH Homo sapiens Q9Y2I1
Pull Down
23386062
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11569 RAB4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab4a NCBI NCBI:5867