ELMOD2 - ELMO domain containing 2 Gene

Also Known as 9830169G11Rik

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 255520

About ELMOD2

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:140,524,168-140,553,770 (from NCBI)

This gene has 8 transcripts (splice variants), 213 orthologues and 5 paralogues. Ubiquitous expression in thyroid (RPKM 4.2), adrenal (RPKM 3.3) and 25 other tissues.

Summary

This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in Antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]

ELMOD2 Products (1)

mRNA Protein Name
NM_153702.4 NP_714913.1 ELMO domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
17452337 GOA
Biological Process GO Annotation Evidence References Source
involved in regulation of defense response to virus IDA
IDA: Inferred from direct assay
17452337 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELMOD2 Protein Structure

ELMO_CED12

ELMO_CED12: ELMO/CED-12 family (112 - 270)

  • 0
  • 100
  • 200
  • 293 a.a.
Protein Preferred Names Protein Names

ELMO domain-containing protein 2

  • ELMO/CED-12 domain containing 2

Related Diseases

Diseases Alias
Pulmonary Fibrosis

  • Fibrosis Of Lung
Postinflammatory Pulmonary Fibrosis

  • Post-Inflammatory Pulmonary Fibrosis
Carotid Artery Dissection

  • Dissection Of Carotid Artery
Caplan'S Syndrome

  • Caplan Syndrome

  • Caplan'S Disease

  • Caplans Syndrome

  • Rheumatoid Pneumoconiosis
Interstitial Lung Disease 2

  • Idiopathic Pulmonary Fibrosis

  • Ipf

  • Fibrocystic Pulmonary Dysplasia

  • Pulmonary Fibrosis, Idiopathic

  • Pulmonary Fibrosis, Idiopathic, Susceptibility To

  • Cryptogenic Fibrosing Alveolitis

  • ILD2

  • Idiopathic Pulmonary Fibrosis, Familial

  • Fibrosing Alveolitis, Cryptogenic

  • Uip

  • Fibrosing Alveolitis

  • Interstitial Pneumonitis, Usual

  • Familial Idiopathic Pulmonary Fibrosis

  • Idiopathic Fibrosing Alveolitis, Chronic Form

  • Usual Interstitial Pneumonia

  • Fibrosing Alveolitis Cryptogenic

  • Hamman-Rich Disease

  • Idiopathic Pulmonary Fibrosis Familial

  • Interstitial Pneumonitis Usual

  • Fibrosis Idiopathic Pulmonary

  • Fibrosis, Pulmonary, Idiopathic

  • Hamman-Rich Syndrome

  • Chronic Idiopathic Pulmonary Fibrosis

  • Acute Interstitial Pneumonia

  • Interstitial Pulmonary Fibrosis

  • Ipf - [Idiopathic Pulmonary Fibrosis]

  • Idiopathic Lung Fibrosis

  • Fibrosing Lung Disease

  • Pulmonary Fibrosis Nos

  • Fibrosing Pneumonitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04315 ELMOD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ELMOD2 VGNC VGNC:72126
Mus musculus ELMOD2 MGD MGI:2445165
Felis catus ELMOD2 VGNC VGNC:61819
Bos taurus ELMOD2 VGNC VGNC:28442
Rattus norvegicus ELMOD2 RGD RGD:1587598
Canis familiaris ELMOD2 VGNC VGNC:40313
Others ELMOD2 NCBI