Snai2 - snail family transcriptional repressor 2 Gene

Also Known as Slug

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25554

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in cellular response to Fibroblast Growth Factor stimulus and negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 2D and piebaldism. Orthologous to human SNAI2 (snail family transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Snai2 Products (1)

mRNA Protein Name
NM_013035.2 NP_037167.1 zinc finger protein SNAI2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to fibroblast growth factor stimulus IEP
IEP: Inferred from expression pattern
9182671 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16153441 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein SNAI2

  • Slug, chicken homolog

  • neural crest transcription factor Slug

  • protein snail homolog 2

  • snail family zinc finger 2

  • snail homolog 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147041 Selvigaltin Inhibitor 99.89% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162723 FOSL1 degrader 1 Degrader 99.66% Unkown
HY-RS13471 SNAI2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16305 Snai2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124595 MPT0B098 Inhibitor / Unkown
HY-RS26608 Snai2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snai2 NCBI NCBI:6591