Cma1 - chymase 1 Gene

Also Known as MCP3P; Mcpt5

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25627

Summary

Enables peptide binding activity and serine-type endopeptidase activity. Involved in several processes, including cellular response to glucose stimulus; midbrain development; and positive regulation of angiogenesis. Located in extracellular region. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; hypertrophic cardiomyopathy; and sarcoidosis. Orthologous to human CMA1 (chymase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cma1 Products (1)

mRNA Protein Name
NM_013092.2 NP_037224.1 chymase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables peptide binding IMP
IMP: Inferred from mutant phenotype
15869764 RGD
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
12444981 RGD
enables serine-type endopeptidase activity IMP
IMP: Inferred from mutant phenotype
15869764 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucose stimulus IEP
IEP: Inferred from expression pattern
17483239 RGD
involved in midbrain development IEP
IEP: Inferred from expression pattern
21396433 RGD
involved in peptide metabolic process IEP
IEP: Inferred from expression pattern
15265236 RGD
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
15723097 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
12900423 RGD
involved in protein processing IDA
IDA: Inferred from direct assay
15869764 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
15265236 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chymase

  • alpha-chymase

  • chymase 1, mast cell

  • mast cell protease 3

  • mast cell protease 5

  • mast cell protease III

  • rMCP-3

  • rMCP-5

  • rMCP-III

Orthologs Information

Species Symbol Source ID
Homo sapiens Cma1 NCBI NCBI:1215