SNED1 - sushi, nidogen and EGF like domains 1 Gene

Also Known as SST3; Snep; IRE-BP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25992

About SNED1

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:240,997,650-241,095,568 (from NCBI)

This gene has 12 transcripts (splice variants), 189 orthologues and 7 paralogues. Ubiquitous expression in ovary (RPKM 13.4), gall bladder (RPKM 12.9) and 24 other tissues.

Summary

Predicted to enable Notch binding activity. Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

SNED1 Products (1)

mRNA Protein Name
NM_001080437.3 NP_001073906.1 sushi, nidogen and EGF-like domain-containing protein 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
33724335 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNED1 Protein Structure

NIDO

NIDO: Nidogen-like (168 - 257)

EGF

EGF: EGF-like domain (272 - 307)

EGF

EGF: EGF-like domain (315 - 344)

hEGF

hEGF: Human growth factor-like EGF (372 - 384)

EGF

EGF: EGF-like domain (391 - 421)

EGF

EGF: EGF-like domain (433 - 461)

EGF

EGF: EGF-like domain (545 - 575)

EGF

EGF: EGF-like domain (584 - 614)

EGF

EGF: EGF-like domain (623 - 653)

EGF

EGF: EGF-like domain (757 - 787)

EGF

EGF: EGF-like domain (795 - 823)

EGF

EGF: EGF-like domain (833 - 861)

hEGF

hEGF: Human growth factor-like EGF (890 - 902)

fn3

fn3: Fibronectin type III domain (908 - 987)

fn3

fn3: Fibronectin type III domain (1007 - 1083)

fn3

fn3: Fibronectin type III domain (1106 - 1184)

EGF

EGF: EGF-like domain (1311 - 1341)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1413 a.a.
Protein Preferred Names Protein Names

sushi, nidogen and EGF-like domain-containing protein 1

  • insulin responsive sequence DNA binding protein-1

Related Diseases

Diseases Alias
Cortical Thymoma

  • Polygonal Cell Thymoma

  • Thymoma, Cortical

  • Thymoma, Type B2
Hormone Producing Pituitary Cancer

  • Growth Hormone Producing Pituitary Tumor

  • Pituitary Tumors, Hormone Producing

  • Somatotropinoma

  • Growth Hormone-Producing Pituitary Gland Neoplasm
Hyperpituitarism
Growth Hormone Secreting Pituitary Adenoma

  • Somatotroph Adenoma

  • Growth Hormone-Secreting Pituitary Adenoma

  • Growth Hormone Producing Adenoma Of The Pituitary

  • Growth Hormone Secreting Adenoma Of Pituitary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13489 SNED1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SNED1 VGNC VGNC:80361
Rattus norvegicus SNED1 RGD RGD:1566079
Mus musculus SNED1 MGD MGI:3045960
Canis familiaris SNED1 VGNC VGNC:59094
Macaca mulatta SNED1 VGNC VGNC:99404
Bos taurus SNED1 VGNC VGNC:106938