Aldh1a3 - aldehyde dehydrogenase 1 family, member A3 Gene

Also Known as Aldh6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266603

Summary

Enables aldehyde dehydrogenase [NAD(P)+] activity. Involved in several processes, including kidney development; pituitary gland development; and retinoic acid biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in isolated microphthalmia 8. Orthologous to human ALDH1A3 (aldehyde dehydrogenase 1 family member A3). [provided by Alliance of Genome Resources, Apr 2022]

Aldh1a3 Products (1)

mRNA Protein Name
NM_153300.2 NP_695212.2 aldehyde dehydrogenase family 1 member A3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables aldehyde dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
11306051 RGD
Biological Process GO Annotation Evidence References Source
involved in kidney development IEP
IEP: Inferred from expression pattern
15567713 RGD
involved in pituitary gland development IEP
IEP: Inferred from expression pattern
17180597 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
11306051 RGD
involved in retinoic acid biosynthetic process IEP
IEP: Inferred from expression pattern
15950969 RGD
involved in retinoic acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
21138835 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aldehyde dehydrogenase family 1 member A3

  • RALDH-3

  • aldehyde dehydrogenase 6

  • aldehyde dehydrogenase family 1, subfamily A3

  • ralDH3

  • retinaldehyde dehydrogenase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W015273A trans-3-Indoleacrylic acid Inhibitor 99.77% Unkown
HY-125085 ALDH3A1-IN-3 Inhibitor 99.43% Unkown
HY-122912 ALDH1A inhibitor 673A 99.15% Unkown
HY-144667 ALDH1A3-IN-1 Inhibitor 98.05% Unkown
HY-135841 CM010 Inhibitor 99.70% Unkown
HY-W017186 ALDH1A3-IN-3 Inhibitor 99.26% Unkown
HY-164781 KOTX1 Inhibitor 98.94% Unkown
HY-169884 MCI-INI-3 Inhibitor 99.23% Unkown
HY-144669 ALDH1A3-IN-2 Inhibitor 99.85% Unkown
HY-128299 ALDH3A1-IN-4 Inhibitor 99.91% Unkown
HY-RS23346 Aldh1a3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-158026 ALDH1A1-IN-5 Inhibitor / Unkown
HY-159111 KS124 / Unkown
HY-RS00564 ALDH1A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-169883 PKM2-IN-7 Inhibitor / Unkown
HY-RS16904 Aldh1a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh1a3 NCBI NCBI:220