2. Gene
  3. SEC14L3 - SEC14 like lipid binding 3 Gene

SEC14L3 - SEC14 like lipid binding 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TAP2

Gene ID: 266629 | Gene type: protein coding

About SEC14L3

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:30,447,661-30,472,017 (from NCBI)

This gene has 7 transcripts (splice variants), 248 orthologues and 6 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

SEC14L3 Products(5)

mRNA Protein Name
NM_001257378.2 NP_001244307.1 SEC14-like protein 3 isoform 2
NM_001257379.2 NP_001244308.1 SEC14-like protein 3 isoform 3
NM_001257382.2 NP_001244311.1 SEC14-like protein 3 isoform 3
NM_001376914.1 NP_001363843.1 SEC14-like protein 3 isoform 4
NM_174975.5 NP_777635.1 SEC14-like protein 3 isoform 1

SEC14L3 Protein Structure

CRAL_TRIO_N

CRAL_TRIO_N: CRAL/TRIO, N-terminal domain (14 - 59)

CRAL_TRIO

CRAL_TRIO: CRAL/TRIO domain (79 - 244)

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Protein Preferred Names Protein Names

SEC14-like protein 3

SEC14-like 3

Related Diseases

Diseases Alias
Palindromic Rheumatism

Hench'S Syndrome

Hench-Rosenberg Syndrome

Palindromic Rheumatism Syndrome

Palindromic Arthritis
Bardet-Biedl Syndrome 13

BBS13

Bardet-Biedl Syndrome, Type 13
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12608 SEC14L3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SEC14L3 VGNC VGNC:53918
Rattus norvegicus SEC14L3 RGD RGD:620812
Mus musculus SEC14L3 MGD MGI:3617848
Macaca mulatta SEC14L3 VGNC VGNC:77270
Felis catus SEC14L3 VGNC VGNC:80483