Scube3 - signal peptide, CUB domain, EGF-like 3 Gene

Also Known as CEGF3; D030038I21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268935

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within positive regulation of smoothened signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in cell surface and extracellular space. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; integumental system; and nose. Orthologous to human SCUBE3 (signal peptide, CUB domain and EGF like domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Scube3 Products (2)

mRNA Protein Name
NM_001004366.2 NP_001004366.1 signal peptide, CUB and EGF-like domain-containing protein 3 isoform 1 precursor
NM_001368734.1 NP_001355663.1 signal peptide, CUB and EGF-like domain-containing protein 3 isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
33308444 MGI
acts upstream of or within positive regulation of smoothened signaling pathway IDA
IDA: Inferred from direct assay
25639508 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

signal peptide, CUB and EGF-like domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS21191 Scube3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12573 SCUBE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27707 Scube3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scube3 NCBI NCBI:222663