GLG1 - golgi glycoprotein 1 Gene

Also Known as CFR-1; ESL-1; MG160; MG-160

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2734

About GLG1

Cytogenetic location: 16q23.1 Genomic coordinates (GRCh38): 16:74,447,440-74,607,114 (from NCBI)

This gene has 14 transcripts (splice variants) and 284 orthologues. Ubiquitous expression in ovary (RPKM 26.0), testis (RPKM 23.5) and 25 other tissues.

Summary

Predicted to enable Fibroblast Growth Factor binding activity. Predicted to act upstream of or within several processes, including negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; and regulation of chondrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

GLG1 Products (3)

mRNA Protein Name
NM_001145666.2 NP_001139138.1 Golgi apparatus protein 1 isoform 2 precursor
NM_001145667.2 NP_001139139.1 Golgi apparatus protein 1 isoform 3 precursor
NM_012201.6 NP_036333.2 Golgi apparatus protein 1 isoform 1 precursor

GLG1 Protein Structure

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (154 - 210)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (215 - 273)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (291 - 345)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (349 - 412)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (418 - 470)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (479 - 536)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (540 - 603)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (613 - 667)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (670 - 728)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (732 - 786)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (800 - 855)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (858 - 910)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (915 - 978)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (983 - 1038)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (1046 - 1100)

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  • 1000
  • 1179 a.a.
Protein Preferred Names Protein Names

Golgi apparatus protein 1

  • E-selectin ligand 1

Related Diseases

Diseases Alias
Algoneurodystrophy

  • Reflex Sympathetic Dystrophy

  • Algoneurodystrophy, Site Unspecified
Pontocerebellar Hypoplasia, Type 2e

  • Pontocerebellar Hypoplasia Type 2

  • Pontocerebellar Hypoplasia Type 2e

  • Pch2

  • PCH2E

  • Progressive Microcephaly From Birth Extrapyramidal Dyskinesia Chorea Epilepsy

  • Pontocerebellar Hypoplasia 2e

  • Pcca2

  • Progressive Cerebello-Cerebral Atrophy Type 2

  • Doid:0112328

  • Hypoplasia, Pontocerebellar, Type 2e

  • Pontocerebellar Hypoplasia, Type 2d

  • Pontocerebellar Hypoplasia Type 2a
Trichinosis

  • Trichinellosis

  • Human Trichinellosis

  • Trichiniasis

  • Trichinella Spiralis Infection

  • Infection With Trichinella

  • Trichinelliasis

  • Trichinella Spiralis Infestation
Amyotrophic Lateral Sclerosis 1

  • Amyotrophic Lateral Sclerosis

  • ALS

  • Lou Gehrig Disease

  • Amyotrophic Lateral Sclerosis Type 1

  • Charcot Disease

  • ALS1

  • Amyotrophic Lateral Sclerosis, Susceptibility To

  • Fals

  • Lou Gehrig'S Disease

  • Mnd

  • Motor Neuron Disease

  • Familial Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis 1, Familial

  • Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

  • Motor Neuron Disease, Bulbar

  • Motor Neurone Disease

  • Amyotrophic Lateral Sclerosis With Dementia

  • Dementia With Amyotrophic Lateral Sclerosis

  • Motor Neuron Disease, Amyotrophic Lateral Sclerosis

  • Sclerosis, Lateral, Amyotrophic

  • Sclerosis, Lateral, Amyotrophic, Type 1

  • Amyotrophic Sclerosis

  • Als - [Amyotrophic Lateral Sclerosis]

  • Wasting Palsy

  • Amyotrophic Paralysis

  • Amyotrophy Lateral Sclerosis

  • Wasting Paralysis

  • Spinal Progressive Amyotrophy

  • Progressive Atrophic Paralysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05471 GLG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21348 Glg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27867 Glg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GLG1 VGNC VGNC:29398
Rattus norvegicus GLG1 RGD RGD:69345
Mus musculus GLG1 MGD MGI:104967
Macaca mulatta GLG1 VGNC VGNC:73068
Felis catus GLG1 VGNC VGNC:62577
Canis familiaris GLG1 VGNC VGNC:41255
Others GLG1 NCBI