Depdc5 - DEP domain containing 5 Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 277854
Summary
Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of Autophagy. Located in cytosol and perinuclear region of cytoplasm. Is expressed in branchial arch; genitourinary system; limb; and peripheral nervous system. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). [provided by Alliance of Genome Resources, Apr 2022]
Depdc5 Products (17)
| mRNA | Protein | Name |
|---|---|---|
| NM_001025426.3 | NP_001020597.1 | GATOR complex protein DEPDC5 isoform 1 |
| NM_001170567.2 | NP_001164038.1 | GATOR complex protein DEPDC5 isoform 3 |
| NM_001360014.2 | NP_001346943.1 | GATOR complex protein DEPDC5 isoform 4 |
| NM_001404313.1 | NP_001391242.1 | GATOR complex protein DEPDC5 isoform 3 |
| NM_001404314.1 | NP_001391243.1 | GATOR complex protein DEPDC5 isoform 1 |
| NM_001404315.1 | NP_001391244.1 | GATOR complex protein DEPDC5 isoform 5 |
| NM_001404316.1 | NP_001391245.1 | GATOR complex protein DEPDC5 isoform 6 |
| NM_001404317.1 | NP_001391246.1 | GATOR complex protein DEPDC5 isoform 6 |
| NM_001404318.1 | NP_001391247.1 | GATOR complex protein DEPDC5 isoform 7 |
| NM_001404319.1 | NP_001391248.1 | GATOR complex protein DEPDC5 isoform 8 |
| NM_001404320.1 | NP_001391249.1 | GATOR complex protein DEPDC5 isoform 8 |
| NM_001404332.1 | NP_001391261.1 | GATOR complex protein DEPDC5 isoform 9 |
| NM_001404333.1 | NP_001391262.1 | GATOR complex protein DEPDC5 isoform 9 |
| NM_001404334.1 | NP_001391263.1 | GATOR complex protein DEPDC5 isoform 10 |
| NM_001404335.1 | NP_001391264.1 | GATOR complex protein DEPDC5 isoform 11 |
| NM_001404336.1 | NP_001391265.1 | GATOR complex protein DEPDC5 isoform 11 |
| NM_177786.5 | NP_808454.2 | GATOR complex protein DEPDC5 isoform 2 |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytosol |
IDA
IDA: Inferred from direct assay
|
23542697 | MGI |
| located in perinuclear region of cytoplasm |
IDA
IDA: Inferred from direct assay
|
23542697 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
GATOR complex protein DEPDC5 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS03695 | DEPDC5 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20545 | Depdc5 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27054 | Depdc5 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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