GNL1 - G protein nucleolar 1 (putative) Gene

Also Known as HSR1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2794

About GNL1

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,541,381-30,556,489 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 194 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 17.9), testis (RPKM 13.8) and 25 other tissues.

Summary

The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008]

GNL1 Products (1)

mRNA Protein Name
NM_005275.5 NP_005266.2 guanine nucleotide-binding protein-like 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
17525332 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GNL1 Protein Structure

MMR_HSR1

MMR_HSR1: 50S ribosome-binding GTPase (363 - 418)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 607 a.a.
Protein Preferred Names Protein Names

guanine nucleotide-binding protein-like 1

  • GTP-binding protein HSR1

Related Diseases

Diseases Alias
Multiple Benign Circumferential Skin Creases On Limbs

  • Ccsf

  • Circumferential Skin Creases, Kunze Type

  • Congenital Circumferential Skin Folds

  • Kunze-Riehm Syndrome

  • Kunze Riehm Syndrome

  • Michelin Tire Baby Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05564 GNL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GNL1 MGD MGI:95764
Felis catus GNL1 VGNC VGNC:102431
Macaca mulatta GNL1 VGNC VGNC:104402
Rattus norvegicus GNL1 RGD RGD:1303051
Bos taurus GNL1 VGNC VGNC:57319
Others GNL1 NCBI