SLCO4A1 - solute carrier organic anion transporter family member 4A1 Gene

Homo sapiens

Also known as POAT; OATP1; OATPE; OATP-E; OATP4A1; OATPRP1; SLC21A12

Gene ID: 28231 | Gene type: protein coding

About SLCO4A1

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,642,503-62,690,740 (from NCBI)

This gene has 9 transcripts (splice variants), 208 orthologues and 10 paralogues. Ubiquitous expression in esophagus (RPKM 2.4), endometrium (RPKM 1.6) and 23 other tissues.

Summary

Predicted to enable sodium-independent organic anion transmembrane transporter activity and thyroid hormone transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLCO4A1 Products(1)

mRNA	Protein	Name
NM_016354.4	NP_057438.3	solute carrier organic anion transporter family member 4A1

SLCO4A1 Protein Structure

OATP

Kazal_2

0
200
400
600
722 a.a.

Protein Preferred Names

Protein Names

solute carrier organic anion transporter family member 4A1

OATP-RP1

Related Diseases

Diseases

Alias

Primary Hypertrophic Osteoarthropathy

Pachydermoperiostosis Syndrome	Osteoarthropathy, Primary Hypertrophic
Pachydermoperiostosis Of Nail	Idiopathic Hypertrophic Osteoarthropathy
Pho

Myasthenic Syndrome, Congenital, 1b, Fast-Channel

CMS1B	Congenital Myasthenic Syndrome 1b
Myasthenic Syndrome, Congenital, Fast-Channel	Congenital Myasthenic Syndrome 1b, Fast-Channel
Fccms	Myasthenic Syndrome, Fast-Channel Congenital
Myasthenic Syndrome, Congenital, Type 1b, Fast-Channel	Congenital Myasthenic Syndrome Ib

Intrahepatic Cholestasis Of Pregnancy

Recurrent Intrahepatic Cholestasis Of Pregnancy	Gravidic Intrahepatic Cholestasis
Pregnancy-Related Cholestasis	Icp
Pregnancy Related Cholestasis	Cholestasis, Intrahepatic Of Pregnancy
Familial Intrahepatic Cholestasis Of Pregnancy	Familial Recurrent Intrahepatic Cholestasis Of Pregnancy
Ricp	Obstetric Cholestasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13358	SLCO4A1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS13359	SLCO4C1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLCO4A1	VGNC	VGNC:65447
Bos taurus	SLCO4A1	VGNC	VGNC:34954
Rattus norvegicus	SLCO4A1	RGD	RGD:620228
Macaca mulatta	SLCO4A1	VGNC	VGNC:77599
Mus musculus	SLCO4A1	MGD	MGI:1351866
Canis familiaris	SLCO4A1	VGNC	VGNC:46498

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