1. Gene
  2. GPR4 - G protein-coupled receptor 4 Gene

GPR4 - G protein-coupled receptor 4 Gene

Homo sapiens

Also known as GPR6C.l

Gene ID: 2828 | Gene type: protein coding

About GPR4

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,589,764-45,602,212 (from NCBI)

This gene has 2 transcripts (splice variants), 141 orthologues and 16 paralogues. Broad expression in fat (RPKM 4.0), lung (RPKM 2.3) and 22 other tissues.

Summary

Enables G protein-coupled receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR4 Products(1)

mRNA Protein Name
NM_005282.3 NP_005273.1 G-protein coupled receptor 4

GPR4 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (35 - 286)

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  • 362 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 4

G-protein coupled receptor 19

G-protein coupled receptor 6C.l

Related Diseases

Diseases Alias
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Congenital Central Hypoventilation Syndrome

Cchs

Haddad Syndrome

Ondine Curse

Ondine Syndrome

Congenital Central Hypoventilation

Congenital Central Alveolar Hypoventilation Syndrome

Congenital Failure Of Autonomic Control

Ondine'S Curse

Primary Alveolar Hypoventilation

Ondine-Hirschsprung Disease

Central Congenital Hypoventilation Syndrome

Congenital Ondine Curse

Idiopathic Congenital Central Alveolar Hypoventilation

Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome

Ondine-Hirschsprung Syndrome

Prolactin Producing Pituitary Tumor

Prolactin-Producing Pituitary Gland Carcinoma

Prolactin-Producing Pituitary Tumor

Malignant Prolactin Producing Neoplasm Of Pituitary Gland

Malignant Prolactinoma

Prolactin Producing Pituitary Tumour

Prolactin Secreting Tumor Of Pituitary

Prolactin Secreting Tumour Of Pituitary

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus GPR4 VGNC VGNC:67427
Macaca mulatta GPR4 VGNC VGNC:73136
Canis familiaris GPR4 VGNC VGNC:41435
Rattus norvegicus GPR4 RGD RGD:1311604
Mus musculus GPR4 MGD MGI:2441992
Bos taurus GPR4 VGNC VGNC:29587
Others GPR4 NCBI