GPR20 - G protein-coupled receptor 20 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2843

About GPR20

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:141,356,470-141,367,286 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 223 orthologues and 16 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Located in cytosol and plasma membrane. Is integral component of plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

GPR20 Products (1)

mRNA Protein Name
NM_005293.3 NP_005284.2 G-protein coupled receptor 20

GPR20 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (71 - 297)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 20

  • CTD-3064M3.3

Related Diseases

Diseases Alias
Retinitis Pigmentosa 11

  • RP11

  • Retinitis Pigmentosa-11

  • Retinitis Pigmentosa, Type 11
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

  • Polycystic Kidney Disease 2

  • PKD2

  • Polycystic Kidney Disease, Adult, Type Ii

  • Apkd2

  • Polycystic Kidney Disease, Type 2

  • Adpkd2

  • Adult Polycystic Kidney Disease Type 2

  • Autosomal Dominant Polycystic Kidney Disease 2

  • Pkd-2

  • Polycystic Kidney Disease Adult Type Ii

  • Polycystic Kidney Type 2 Autosomal Dominant Disease

  • Kidney Disease, Polycystic, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05694 GPR20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20939 Gpr20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27456 Gpr20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990578 Anti-GPR20 Antibody 99.78% Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GPR20 RGD RGD:620034
Felis catus GPR20 VGNC VGNC:67420
Bos taurus GPR20 VGNC VGNC:29579
Mus musculus GPR20 MGD MGI:2441803
Canis familiaris GPR20 VGNC VGNC:41425
Macaca mulatta GPR20 VGNC VGNC:104459
Others GPR20 NCBI