2. Gene
  3. GPR20 - G protein-coupled receptor 20 Gene

GPR20 - G protein-coupled receptor 20 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 2843 | Gene type: protein coding

About GPR20

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:141,356,470-141,367,286 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 223 orthologues and 16 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Located in cytosol and plasma membrane. Is integral component of plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

GPR20 Products(1)

mRNA Protein Name
NM_005293.3 NP_005284.2 G-protein coupled receptor 20

GPR20 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (71 - 297)

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  • 358 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 20

CTD-3064M3.3

Related Diseases

Diseases Alias
Retinitis Pigmentosa 11

RP11

Retinitis Pigmentosa-11

Retinitis Pigmentosa, Type 11
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2

PKD2

Polycystic Kidney Disease, Adult, Type Ii

Apkd2

Polycystic Kidney Disease, Type 2

Adpkd2

Adult Polycystic Kidney Disease Type 2

Autosomal Dominant Polycystic Kidney Disease 2

Pkd-2

Polycystic Kidney Disease Adult Type Ii

Polycystic Kidney Type 2 Autosomal Dominant Disease

Kidney Disease, Polycystic, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05694 GPR20 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GPR20 RGD RGD:620034
Felis catus GPR20 VGNC VGNC:67420
Bos taurus GPR20 VGNC VGNC:29579
Mus musculus GPR20 MGD MGI:2441803
Canis familiaris GPR20 VGNC VGNC:41425
Macaca mulatta GPR20 VGNC VGNC:104459