Usp46 - ubiquitin specific peptidase 46 Gene

Also Known as RGD1564808

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289584

Summary

Predicted to enable cysteine-type endopeptidase activity and thiol-dependent Deubiquitinase. Involved in regulation of postsynaptic neurotransmitter receptor internalization. Is active in glutamatergic synapse. Orthologous to human USP46 (ubiquitin specific peptidase 46). [provided by Alliance of Genome Resources, Apr 2022]

Usp46 Products (1)

mRNA Protein Name
NM_001191596.1 NP_001178525.1 ubiquitin carboxyl-terminal hydrolase 46

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
26077708 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IEP
IEP: Inferred from expression pattern
26077708 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
26077708 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26077708 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26077708 RGD
is active in synapse IDA
IDA: Inferred from direct assay
26077708 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 46

  • deubiquitinating enzyme 46

  • ubiquitin specific protease 46

  • ubiquitin thioesterase 46

  • ubiquitin-specific-processing protease 46

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS24179 Usp46 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15557 USP46 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17714 Usp46 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp46 NCBI NCBI:64854