Rbbp8 - RB binding protein 8, endonuclease Gene

Also Known as RIM; CtIP; SAE2; RBBP-8; RGD1308872

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 291787

Summary

Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and single-stranded DNA endodeoxyribonuclease activity. Involved in response to estradiol. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in site of double-strand break. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Orthologous to human RBBP8 (RB binding protein 8, Endonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp8 Products (1)

mRNA Protein Name
NM_001134417.1 NP_001127889.1 DNA endonuclease RBBP8

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15473135 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA endonuclease RBBP8

  • ctBP-interacting protein

  • retinoblastoma binding protein 8

  • sporulation in the absence of SPO11 protein 2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11720 RBBP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20478 Rbbp8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26986 Rbbp8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Rbbp8 NCBI NCBI:5932