Tubb4a - tubulin, beta 4A class IVa Gene

Also Known as Tubb4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29213

Summary

Predicted to enable GTP binding activity and calcium ion binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization; mitotic cell cycle; and negative regulation of microtubule polymerization. Predicted to be located in several cellular components, including axoneme; internode region of axon; and neuronal cell body. Predicted to be active in cytoplasm and microtubule. Used to study demyelinating disease. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 6 and torsion dystonia 4. Orthologous to human TUBB4A (tubulin beta 4A class IVa). [provided by Alliance of Genome Resources, Apr 2022]

Tubb4a Products (1)

mRNA Protein Name
NM_080882.1 NP_543158.1 tubulin beta-4A chain

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-4A chain

  • tubulin, beta 4 class IVa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15255 TUBB4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20612 Tubb4a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27120 Tubb4a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb4a NCBI NCBI:10382