Car4 - carbonic anhydrase 4 Gene

Also Known as Ca4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29242

About Car4

Primary_assembly 10: 69,827,945-69,836,501 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 333 orthologues, 16 paralogues and is associated with 6 phenotypes. Biased expression in Lung (RPKM 349.5), Kidney (RPKM 191.9) and 3 other tissues.

Summary

Enables carbonate dehydratase activity. Involved in animal organ development; response to steroid hormone; and response to xenobiotic stimulus. Located in apical plasma membrane; sarcolemma; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA4 (Carbonic Anhydrase 4). [provided by Alliance of Genome Resources, Apr 2022]

Car4 Products (1)

mRNA Protein Name
NM_019174.3 NP_062047.1 carbonic anhydrase 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carbonate dehydratase activity IDA
IDA: Inferred from direct assay
1533109 RGD
Biological Process GO Annotation Evidence References Source
involved in response to steroid hormone IEP
IEP: Inferred from expression pattern
10569998 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16144999 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
8675662 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
8911968 RGD
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
8911968 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Car4 Protein Structure

alpha_CA_IV_XV_like

alpha_CA_IV_XV_like: cd03117 (46 - 279)

  • 0
  • 100
  • 200
  • 309 a.a.
Protein Preferred Names Protein Names

carbonic anhydrase 4

  • CA-IV

  • carbonate dehydratase IV

  • carbonic anhydrase IV

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01770 CA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01911 Car4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01912 Car4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown