Kif7 - kinesin family member 7 Gene

Predicted to enable several functions, including ATP hydrolysis activity; identical protein binding activity; and microtubule binding activity. Predicted to be involved in microtubule-based movement; negative regulation of smoothened signaling pathway; and positive regulation of smoothened signaling pathway. Predicted to act upstream of or within aorta development; cardiac septum development; and coronary vasculature development. Predicted to be located in ciliary basal body. Predicted to be part of Kinesin complex. Predicted to be active in microtubule. Biomarker of congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in acrocallosal syndrome; cleft lip; and hydrolethalus syndrome 2. Orthologous to human KIF7 (Kinesin family member 7). [provided by Alliance of Genome Resources, Apr 2022]