Acta1 - actin, alpha 1, skeletal muscle Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29437

Summary

Predicted to enable ATP binding activity. Involved in several processes, including response to lithium ion; response to steroid hormone; and skeletal muscle fiber adaptation. Predicted to be located in several cellular components, including filopodium; lamellipodium; and sarcomere. Predicted to be part of dynactin complex. Predicted to be active in actin filament; stress fiber; and striated muscle thin filament. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 3. Orthologous to human ACTA1 (actin alpha 1, skeletal muscle). [provided by Alliance of Genome Resources, Apr 2022]

Acta1 Products (1)

mRNA Protein Name
NM_019212.3 NP_062085.1 actin, alpha skeletal muscle

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to potassium ion IEP
IEP: Inferred from expression pattern
17146758 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
12704188 RGD
involved in response to steroid hormone IEP
IEP: Inferred from expression pattern
14993121 RGD
involved in skeletal muscle fiber adaptation IEP
IEP: Inferred from expression pattern
16428321 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin, alpha skeletal muscle

  • actin alpha 1

  • alpha-actin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00213 ACTA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22375 Acta1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28899 Acta1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acta1 NCBI NCBI:58