Tesk1 - testis associated actin remodelling kinase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29460

Summary

Enables protein C-terminus binding activity; protein kinase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of protein phosphorylation; positive regulation of stress fiber assembly; and spermatogenesis. Located in perinuclear region of cytoplasm. Colocalizes with cytoplasmic vesicle. Orthologous to human TESK1 (testis associated actin remodelling kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tesk1 Products (1)

mRNA Protein Name
NM_031578.2 NP_113766.1 dual specificity testis-specific protein kinase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11555644 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
11555644 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
18216281 RGD
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
8537404 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein autophosphorylation IDA
IDA: Inferred from direct assay
18216281 RGD
involved in negative regulation of protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
18216281 RGD
involved in positive regulation of stress fiber assembly IDA
IDA: Inferred from direct assay
18216281 RGD
involved in regulation of protein localization IDA
IDA: Inferred from direct assay
18216281 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
8537404 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22302232 RGD
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
18216281 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22302232 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity testis-specific protein kinase 1

  • testicular protein kinase 1

  • testis specific protein kinase 1

  • testis-specific kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14380 TESK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22856 Tesk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29370 Tesk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tesk1 NCBI NCBI:7016