Slc6a6 - solute carrier family 6 member 6 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29464

Summary

Enables gamma-aminobutyric acid transmembrane transporter activity; taurine binding activity; and taurine:sodium symporter activity. Involved in gamma-aminobutyric acid import; import across plasma membrane; and taurine transport. Located in dendrite; neuronal cell body; and plasma membrane. Part of plasma membrane protein complex. Orthologous to human SLC6A6 (solute carrier family 6 member 6). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a6 Products (1)

mRNA Protein Name
NM_017206.2 NP_058902.1 sodium- and chloride-dependent taurine transporter

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gamma-aminobutyric acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
18501699 RGD
enables gamma-aminobutyric acid transmembrane transporter activity IGI
IGI: Inferred from genetic interaction
29491210 RGD
enables gamma-aminobutyric acid:sodium:chloride symporter activity IDA
IDA: Inferred from direct assay
18501699 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
29491210 RGD
enables taurine binding IDA
IDA: Inferred from direct assay
1435737 RGD
enables taurine:sodium symporter activity IDA
IDA: Inferred from direct assay
1435737 RGD
Biological Process GO Annotation Evidence References Source
involved in gamma-aminobutyric acid import IDA
IDA: Inferred from direct assay
18501699 RGD
involved in gamma-aminobutyric acid import IGI
IGI: Inferred from genetic interaction
29491210 RGD
involved in import across plasma membrane IGI
IGI: Inferred from genetic interaction
29491210 RGD
involved in taurine transmembrane transport IDA
IDA: Inferred from direct assay
18501699 RGD
involved in taurine transmembrane transport IMP
IMP: Inferred from mutant phenotype
1435737 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
25004465 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
25004465 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
18501699 RGD
part of plasma membrane protein complex IPI
IPI: Inferred from physical interaction
29491210 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium- and chloride-dependent taurine transporter

  • Solute carrier 6 ,member 6 (taurine transporter)

  • solute carrier family 6 (neurotransmitter transporter), member 6

  • solute carrier family 6 (neurotransmitter transporter, taurine), member 6

  • taurine/beta-alanine transporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179581 SLC6A19-IN-4 Inhibitor 99.55% Unkown
HY-RS13317 SLC6A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16229 Slc6a6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25565 Slc6a6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a6 NCBI NCBI:6533