Slc10a2 - solute carrier family 10 member 2 Gene

Rattus norvegicus

Also known as ASBT; IBAT; ISBT; ISBAT

Gene ID: 29500 | Gene type: protein coding

About Slc10a2

Primary_assembly 16: 84,374,862-84,409,475 forward strand.mRatBN7.2:CM026989.1

This gene has 2 transcripts (splice variants), 212 orthologues, 6 paralogues and is associated with 8 phenotypes. Biased expression in Kidney (RPKM 2.9), Testes (RPKM 1.9) and 1 other tissue.

Summary

Enables bile acid:sodium symporter activity. Involved in bile acid and bile salt transport. Located in apical plasma membrane and nucleus. Part of Proteasome complex. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc10a2 Products(1)

mRNA	Protein	Name
NM_017222.2	NP_058918.1	ileal sodium/bile acid cotransporter

Slc10a2 Protein Structure

bass

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348 a.a.

Protein Preferred Names

Protein Names

ileal sodium/bile acid cotransporter

Na(+)-dependent ileal bile acid transporter	apical sodium-dependent bile acid transporter
ileal Na(+)/bile acid cotransporter	ileal sodium-dependent bile acid transporter
sodium/taurocholate-cotransporting polypeptide, ileal	solute carrier family 10 (sodium/bile acid cotransporter family), member 2
solute carrier family 10 (sodium/bile acid cotransporter), member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS12986	SLC10A2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS12987	Slc10a2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS12988	Slc10a2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc10a2	NCBI	NCBI:6555

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