Bok - BCL2 family apoptosis regulator BOK Gene

Also Known as Bok-BH3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29884

Summary

Enables BH domain binding activity and protein heterodimerization activity. Involved in several processes, including central nervous system development; male gonad development; and positive regulation of apoptotic process. Located in mitochondrion. Biomarker of hydrocephalus. Orthologous to human BOK (BCL2 family Apoptosis regulator BOK). [provided by Alliance of Genome Resources, Apr 2022]

Bok Products (1)

mRNA Protein Name
NM_017312.2 NP_059008.1 bcl-2-related ovarian killer protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables BH domain binding IPI
IPI: Inferred from physical interaction
9356461 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9356461 RGD
enables protein dimerization activity IPI
IPI: Inferred from physical interaction
9356461 RGD
NOT enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
9804769 RGD
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
9804769 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9356461 RGD
Biological Process GO Annotation Evidence References Source
involved in apoptotic process IDA
IDA: Inferred from direct assay
9356461 RGD
involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
9356461 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
11720903 RGD
involved in oligodendrocyte differentiation IEP
IEP: Inferred from expression pattern
12787069 RGD
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
9356461 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bcl-2-related ovarian killer protein

  • BCL2-related ovarian killer

  • BOK, BCL2 family apoptosis regulator

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18323 Bok Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01570 BOK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24801 Bok Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bok NCBI NCBI:666