GNL2 - G protein nucleolar 2 Gene

Also Known as NGP1; Nog2; Nug2; Ngp-1; HUMAUANTIG

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29889

About GNL2

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:37,566,816-37,595,937 (from NCBI)

This gene has 9 transcripts (splice variants), 204 orthologues and 6 paralogues. Ubiquitous expression in testis (RPKM 19.5), bone marrow (RPKM 14.5) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

GNL2 Products (3)

mRNA Protein Name
NM_001323623.2 NP_001310552.1 nucleolar GTP-binding protein 2 isoform 2
NM_001323624.2 NP_001310553.1 nucleolar GTP-binding protein 2 isoform 3
NM_013285.3 NP_037417.1 nucleolar GTP-binding protein 2 isoform 1

GNL2 Protein Structure

NGP1NT

NGP1NT: NGP1NT (NUC091) domain (43 - 174)

MMR_HSR1

MMR_HSR1: 50S ribosome-binding GTPase (313 - 379)

  • 0
  • 200
  • 400
  • 600
  • 731 a.a.
Protein Preferred Names Protein Names

nucleolar GTP-binding protein 2

  • autoantigen NGP-1

Related Diseases

Diseases Alias
Siberian Tick Typhus

  • North Asian Tick Typhus

  • Manchurian Typhus

  • North Asian Tick Fever

  • Rickettsia Sibirica Spotted Fever

  • Spotted Fever Group Rickettsiosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05565 GNL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22192 Gnl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28714 Gnl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GNL2 VGNC VGNC:29472
Canis familiaris GNL2 VGNC VGNC:41326
Macaca mulatta GNL2 VGNC VGNC:73037
Felis catus GNL2 VGNC VGNC:62625
Rattus norvegicus GNL2 RGD RGD:1305006
Mus musculus GNL2 MGD MGI:2385207
Others GNL2 NCBI