Mycn - MYCN proto-oncogene, bHLH transcription factor Gene

Also Known as Nmyc; N-myc; Nmuc1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 298894

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and kinase binding activity. Predicted to be involved in negative regulation of Reactive Oxygen Species metabolic process and regulation of gene expression. Predicted to act upstream of or within several processes, including embryonic digit morphogenesis; negative regulation of astrocyte differentiation; and skeletal system morphogenesis. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in Feingold syndrome. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Mycn Products (1)

mRNA Protein Name
NM_001013096.2 NP_001013114.2 N-myc proto-oncogene protein
Protein Preferred Names Protein Names

N-myc proto-oncogene protein

  • Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc)

  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog

  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-11103 Sitaxsentan sodium 98.83% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-117286 (S)-JQ-35 99.46% Phase 1

Pre-clinical Phase

Bioactive Molecules (22)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145765 JQAD1 98.24% Unkown
HY-156443 YG1702 Inhibitor 99.94% Unkown
HY-124447 BTYNB 98.0% Unkown
HY-112273 CD532 Inhibitor 98.86% Unkown
HY-144878 VPC-70619 Inhibitor 99.93% Unkown
HY-171767 SK2188 99.87% Unkown
HY-171768 SK2187 Degrader 95.81% Unkown
HY-168439 HLB-0532259 98.30% Unkown
HY-112273A CD532 hydrochloride Inhibitor 99.62% Unkown
HY-171769 dAurAB2 Degrader 98.61% Unkown
HY-158062 LC-1-40 / Unkown
HY-152032 LSD1-IN-23 Inhibitor / Unkown
HY-179375 LCI133 Inhibitor / Unkown
HY-179640 SK4454 Degrader / Unkown
HY-179641 SK5527 Degrader / Unkown
HY-181442 CK2-TN03 98.02% Unkown
HY-181601 NPD15261 Inducer / Unkown
HY-186247 N-Myc-IN-1 / Unkown
HY-RS08884 MYCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181568 PROTAC Aurora A Degrader-1 / Unkown
HY-RS17293 Mycn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23748 Mycn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mycn NCBI NCBI:4613