ESRRB - estrogen-related receptor beta Gene

Rattus norvegicus

Also known as Err2; Errb

Gene ID: 299210 | Gene type: protein coding

About ESRRB

Primary_assembly 6: 106,008,095-106,160,791 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 264 orthologues, 8 paralogues and is associated with 6 phenotypes. Biased expression in Kidney (RPKM 39.9), Heart (RPKM 38.6) and 3 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in positive regulation of glycogen biosynthetic process and positive regulation of glycolytic process. Predicted to be located in condensed chromosome; cytosol; and nucleoplasm. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

ESRRB Products(1)

mRNA	Protein	Name
NM_001008516.3	NP_001008516.3	steroid hormone receptor ERR2

ESRRB Protein Structure

NR_DBD_ERR

NR_LBD_ERR

0
100
200
300
400
510 a.a.

Protein Preferred Names

Protein Names

steroid hormone receptor ERR2

ERR-beta	estrogen receptor-like 2
nuclear receptor subfamily 3 group B member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS04540	ESRRB Human Pre-designed siRNA Set A	/	Unkown
HY-RS04541	Esrrb Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS04542	ESRRB Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	ESRRB	NCBI	NCBI:2103

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