ESRRB - estrogen-related receptor beta Gene

Also Known as Err2; Errb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 299210

About ESRRB

Primary_assembly 6: 106,008,095-106,160,791 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 264 orthologues, 8 paralogues and is associated with 6 phenotypes. Biased expression in Kidney (RPKM 39.9), Heart (RPKM 38.6) and 3 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in positive regulation of glycogen biosynthetic process and positive regulation of glycolytic process. Predicted to be located in condensed chromosome; cytosol; and nucleoplasm. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

ESRRB Products (1)

mRNA Protein Name
NM_001008516.3 NP_001008516.3 steroid hormone receptor ERR2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of glycogen biosynthetic process IDA
IDA: Inferred from direct assay
24481529 RGD
involved in positive regulation of glycolytic process IDA
IDA: Inferred from direct assay
24481529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ESRRB Protein Structure

NR_DBD_ERR

NR_DBD_ERR: cd07170 (174 - 269)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (288 - 507)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 510 a.a.
Protein Preferred Names Protein Names

steroid hormone receptor ERR2

  • ERR-beta

  • estrogen receptor-like 2

  • nuclear receptor subfamily 3 group B member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04540 ESRRB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04541 Esrrb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04542 ESRRB Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ESRRB NCBI NCBI:2103