Rrm2b - ribonucleotide reductase regulatory TP53 inducible subunit M2B Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 299976

Summary

Predicted to enable identical protein binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in response to amine. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5; mitochondrial DNA depletion syndrome 8a; and mitochondrial DNA depletion syndrome 8b. Orthologous to human RRM2B (ribonucleotide reductase regulatory TP53 inducible subunit M2B). [provided by Alliance of Genome Resources, Apr 2022]

Rrm2b Products (1)

mRNA Protein Name
NM_001130543.1 NP_001124015.1 ribonucleoside-diphosphate reductase subunit M2 B

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to amine IEP
IEP: Inferred from expression pattern
14587038 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribonucleoside-diphosphate reductase subunit M2 B

  • ribonucleotide reductase M2 B (TP53 inducible)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12287 RRM2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21746 Rrm2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28263 Rrm2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rrm2b NCBI NCBI:50484